The Atlas of Immunoglobulin Repertoires


The Atlas of Immune Repertoires (The AIR) is a collection of CDR3 from T and B cell receptors (BCR and TCR). CDR3s are assembled from 8,555 human RNA-seq samples across 544 individuals from 53 tissues from the Genotype-Tissue Expression (GTEx v6) project using ImReP.

The AIR has the largest collection of CDR3 sequences (n=3.8 million) and tissue types (n=53).

To facilitate its use by others, the data available in an easily accessible online resource available at


This atlas was prepared by  Serghei Mangul. If you have any questions, please send an email to Serghei Mangul ( . To report a bug please use github.



The AIR 0.1 release 01/19/2017

The first public release of The AIR is available.

The current release contains public clonotypes ( i.e. CDR3s shared by at least two individuals) for each of the B and T cell receptor chains:

Because this is the first release, the documentation is very limited. We plan to update it frequently. If you have any questions about how to use The AIR, please contact Serghei Mangul (



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